Lipenil

Lipenil may be available in the countries listed below.

Ingredient matches for Lipenil

Simvastatin

Simvastatin is reported as an ingredient of Lipenil in the following countries:

• Italy

International Drug Name Search

Allylestrenol

Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

G03DC01

CAS registry number (Chemical Abstracts Service)

0000432-60-0

Chemical Formula

C21-H32-O

Molecular Weight

300

Therapeutic Category

Progestin

Chemical Name

Estr-4-en-17-ol, 17-(2-propenyl)-, (17ß)-

Foreign Names

• Allylestrenolum (Latin)
• Allylestrenol (German)
• Allylestrénol (French)
• Alilestrenol (Spanish)

Generic Names

• Allilestrenolo (OS: DCIT)
• Allylestrenol (OS: BAN)
• Allylestrénol (OS: DCF)
• Allyloestrenol (IS)

Brand Names

• Alilestrenol
  Terapia, Romania



• Arandal
  Taisho Yakuhin, Japan



• Aroserine
  Fuji Yakuhin, Japan



• Cobarenol
  Kobayashi Kako, Japan



• Elmolan
  Sawai Seiyaku, Japan



• Gravynon
  Kimia Farma, Indonesia



• Lestron
  Bernofarm, Indonesia



• Maintane Tab.
  Jagson Pal, India



• Meieston
  Towa Yakuhin, Japan



• Pelias
  Shinyaku, Japan



• Perselin
  Schering-Plough, Japan



• Preabor
  Sanbe, Indonesia



• Pregnolin
  Dexa Medica, Indonesia



• Pregtenol
  Dexa Medica, Indonesia



• Premaston
  Kalbe, Indonesia; Kalbe Farma, Sri Lanka; Kalbe Farma, Myanmar



• Prestrenol
  Interbat, Indonesia



• Profar
  Organon, India



• Progeston
  Meprofarm, Indonesia



• Protanon
  Yu Sheng, Taiwan



• Salmichol
  Hyzon Seiyaku, Japan



• Shegest
  Solitaire, India



• Turinal
  Gedeon Richter, Singapore

International Drug Name Search

Glossary

BAN	British Approved Name
DCF	Dénomination Commune Française
DCIT	Denominazione Comune Italiana
IS	Inofficial Synonym
OS	Official Synonym
Rec.INN	Recommended International Nonproprietary Name (World Health Organization)

Click for further information on drug naming conventions and International Nonproprietary Names.

Teveten Comp.

Teveten Comp. may be available in the countries listed below.

Ingredient matches for Teveten Comp.

Eprosartan

Eprosartan mesilate (a derivative of Eprosartan) is reported as an ingredient of Teveten Comp. in the following countries:

• Denmark


• Norway


• Sweden

Hydrochlorothiazide

Hydrochlorothiazide is reported as an ingredient of Teveten Comp. in the following countries:

• Denmark


• Norway


• Sweden

International Drug Name Search

Paroxetine A

Paroxetine A may be available in the countries listed below.

Ingredient matches for Paroxetine A

Paroxetine

Paroxetine hydrochloride (a derivative of Paroxetine) is reported as an ingredient of Paroxetine A in the following countries:

• Netherlands

International Drug Name Search

Lorfan

Lorfan may be available in the countries listed below.

Ingredient matches for Lorfan

Levallorphan

Levallorphan tartrate (a derivative of Levallorphan) is reported as an ingredient of Lorfan in the following countries:

• Japan

International Drug Name Search

Sandoz Allopurinol

Sandoz Allopurinol may be available in the countries listed below.

Ingredient matches for Sandoz Allopurinol

Allopurinol

Allopurinol is reported as an ingredient of Sandoz Allopurinol in the following countries:

• South Africa

International Drug Name Search

Butapap

Ingredient matches for Butapap

Butalbital

Butalbital is reported as an ingredient of Butapap in the following countries:

• United States

Paracetamol

Paracetamol is reported as an ingredient of Butapap in the following countries:

• United States

International Drug Name Search

bevacizumab

Generic Name: bevacizumab (bev a CIZ oo mab)

Brand Names: Avastin

What is bevacizumab?

Bevacizumab is a cancer medicine that interferes with the growth of cancer cells and slows their growth and spread in the body.

Bevacizumab is used to treat a certain type of brain tumor, and certain types of cancers of the kidney, lung, colon and rectum. It is usually given as part of a combination of cancer medicines.

Bevacizumab may also be used for purposes not listed in this medication guide.

What is the most important information I should know about bevacizumab?

Treatment with bevacizumab may cause you to have problems with wound healing, which could result in bleeding or infection. If you need to have any type of surgery, you will need to stop receiving bevacizumab at least 4 weeks ahead of time. Do not start using bevacizumab for at least 4 weeks after surgery, or until your surgical incision heals.

Before being treated with bevacizumab, tell your doctor if you have a bleeding or blood-clotting disorder, heart disease, congestive heart failure, high blood pressure, or a history of heart attack, stroke, blood clots, or stomach or intestinal bleeding (including perforation).

Some people receiving a bevacizumab injection have had a reaction to the infusion (when the medicine is injected into the vein). Tell your caregiver right away if you feel dizzy, nauseated, light-headed, sweaty, itchy, or have a fast heartbeat, chills, wheezing, or chest pain during the injection.

Call your doctor at once if you have: any unusual bleeding or bruising, blood in your urine or stools, coughing up blood, any bleeding that will not stop, severe stomach pain with fever and vomiting, sudden numbness or weakness, leg pain or swelling, chest pain, severe headache, problems with speech or balance, swelling or rapid weight gain, urinating less than usual, loss of bladder or bowel control, or missed menstrual periods.

Bevacizumab can cause a rare but serious neurologic disorder affecting the brain. Symptoms include headache, confusion, vision problems, feeling very weak or tired, fainting, and seizure (blackout or convulsions). These rare symptoms may occur within hours of your first dose of bevacizumab, or they may not appear for up to a year after your treatment started. Call your doctor at once if you have any of these side effects.

To be sure this medication is not causing harmful effects, your blood pressure will need to be checked often. Your urine may also need to be tested. Visit your doctor regularly.

Bevacizumab may cause a woman's ovaries to stop working correctly. Symptoms of ovarian failure include 3 or more missed menstrual periods in a row. This may affect your fertility (ability to have children). Talk to your doctor about your specific risks.

What should I discuss with my healthcare provider before receiving bevacizumab?

You should not use bevacizumab if you are allergic to it, or if you have:

• 
  

  untreated or uncontrolled high blood pressure;

  
  


• 
  

  severe or uncontrolled bleeding;

  
  


• 
  

  an open skin wound;

  
  


• 
  

  an open surgical incision;

  
  


• 
  

  if you have had surgery within the past 4 weeks (28 days);

  
  


• 
  

  if you have recently been coughing up blood; or

  
  


• 
  

  if you plan to have surgery within the next 4 weeks (28 days).

  
  

To make sure you can safely receive bevacizumab, tell your doctor if you have any of these other conditions:

• 
  

  a bleeding or blood-clotting disorder;

  
  


• 
  

  a history of stomach or intestinal bleeding;

  
  


• 
  

  a history of perforation (a hole or tear) in your esophagus, stomach, or intestines;

  
  


• 
  

  heart disease, congestive heart failure;

  
  


• 
  

  high blood pressure; or

  
  


• 
  

  a history of heart attack, stroke, or blood clots.

  
  

FDA pregnancy category C. It is not known whether bevacizumab will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. Bevacizumab may cause a woman's ovaries to stop working correctly. Symptoms of ovarian failure include 3 or more missed menstrual periods in a row. This may affect your fertility (ability to have children). Talk to your doctor about your specific risks. It is not known whether bevacizumab passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are being treated with bevacizumab. Older adults may be more likely to have side effects from this medication.

How is bevacizumab used?

Treatment with bevacizumab may cause you to have problems with wound healing, which could result in bleeding or infection. If you need to have any type of surgery, you will need to stop receiving bevacizumab at least 4 weeks ahead of time. Do not start using bevacizumab for at least 4 weeks after surgery, or until your surgical incision heals.

Bevacizumab is injected into a vein through an IV. You will receive this injection in a clinic or hospital setting. Bevacizumab must be given slowly, and the IV infusion can take up to 90 minutes to complete.

Bevacizumab is usually given once every 2 weeks.

To be sure this medication is not causing harmful effects, your blood pressure will need to be checked often. Your urine may also need to be tested. Visit your doctor regularly.

Bevacizumab must be stored in a refrigerator and kept from freezing. Bevacizumab bottles should never be shaken.

What happens if I miss a dose?

Call your doctor for instructions if you miss an appointment for your bevacizumab injection.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of bevacizumab may cause a severe headache.

What should I avoid while using bevacizumab?

Avoid activities that may increase your risk of bleeding or injury. Use extra care to prevent bleeding while shaving or brushing your teeth.

Bevacizumab side effects

Bevacizumab can cause a rare but serious neurologic disorder affecting the brain. Symptoms include headache, confusion, vision problems, feeling very weak or tired, fainting, and seizure (blackout or convulsions). These rare symptoms may occur within hours of your first dose of bevacizumab, or they may not appear for up to a year after your treatment started. Call your doctor at once if you have any of these side effects.

Some people receiving a bevacizumab injection have had a reaction to the infusion (when the medicine is injected into the vein). Tell your caregiver right away if you feel dizzy, nauseated, light-headed, sweaty, or have a headache, wheezing, or chest pain during the injection.

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have a serious side effect such as:

• 
  

  any wound that will not heal;

  
  


• 
  

  severe stomach pain with fever, vomiting, and constipation;

  
  


• 
  

  blood in your urine or stools, vomit that looks like blood or coffee grounds;

  
  


• 
  

  easy bruising, unusual bleeding (nose, mouth, vagina, rectum), purple or red pinpoint spots under your skin, or any bleeding that will not stop;

  
  


• 
  

  fever, chills, body aches, flu symptoms, sores in your mouth and throat;

  
  


• 
  

  sudden numbness or weakness, severe headache, confusion, or problems with vision, speech, or balance;

  
  


• 
  

  pain, swelling, warmth, or redness in one or both legs;

  
  


• 
  

  chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling;

  
  


• 
  

  dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, shortness of breath, uneven heartbeats, seizure);

  
  


• 
  

  puffy eyes, swelling in your stomach, arms, or legs;

  
  


• 
  

  rapid weight gain, urinating less than usual or not at all;

  
  


• 
  

  urine that looks foamy;

  
  


• 
  

  pain or burning when you urinate, loss of bladder or bowel control;

  
  


• 
  

  ongoing vaginal discharge, itching, or other irritation; or

  
  


• 
  

  missed menstrual periods.

  
  

Less serious side effects may include:

• 
  

  mild headache;

  
  


• 
  

  back pain;

  
  


• 
  

  diarrhea, loss of appetite;

  
  


• 
  

  cold symptoms such as stuffy nose, sneezing, sore throat;

  
  


• 
  

  dry or watery eyes;

  
  


• 
  

  dry or flaky skin, hair loss;

  
  


• 
  

  changes in your sense of taste; or

  
  


• 
  

  jaw pain, swelling, numbness, loose teeth, gum infection.

  
  

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Bevacizumab Dosing Information

Usual Adult Dose for Colorectal Cancer:

Initial dose: 5 mg/kg in combination with intravenous fluorouracil-based chemotherapy

The recommended dose of bevacizumab is based on a rate of 5 mg/kg or 10 mg/kg when used in combination with irinotecan, fluorouracil, and leucovorin in the IFL regimen.

The recommended dose of bevacizumab is based on a rate of 10 mg/kg when used in combination with oxaliplatin, folinic acid, and fluorouracil in the FOLFOX4 regimen.

A dose may be given once every 14 days as an IV infusion until disease progression is detected.

The first dose of bevacizumab should be delivered over 90 minutes as an intravenous infusion following chemotherapy. If the first infusion is well tolerated, the second infusion may be administered over 60 minutes. If the 60 minute infusion is well tolerated, all subsequent infusions may be administered over 30 minutes.

Usual Adult Dose for Non-Small Cell Lung Cancer:

For use in combination with carboplatin and paclitaxel for the treatment of non-squamous, non-small cell lung cancer:

Initial dose: 15 mg/kg as an intravenous infusion every 3 weeks

The first dose of bevacizumab should be delivered over 90 minutes as an intravenous infusion following chemotherapy. If the first infusion is well tolerated, the second infusion may be administered over 60 minutes. If the 60 minute infusion is well tolerated, all subsequent infusions may be administered over 30 minutes.

Usual Adult Dose for Breast Cancer:

(Not approved by FDA)

Recommended dose: 10 mg/kg as an IV infusion every 14 days in combination with paclitaxel.

Usual Adult Dose for Glioblastoma Multiforme:

Recommended dose: 10 mg/kg every 2 weeks

Usual Adult Dose for Ovarian Cancer:

15 mg/kg IV every 3 weeks

Usual Adult Dose for Renal Cell Carcinoma:

10 mg/kg IV every 2 weeks in combination with interferon alfa

Usual Pediatric Dose for Solid Tumors:

Monotherapy: 15 mg/kg IV every 2 weeks in 28 day cycles

Combination therapy: 5 to 10 mg/kg IV every 2 weeks as a part of combination chemotherapy regimens

What other drugs will affect bevacizumab?

There may be other drugs that can interact with bevacizumab. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

More bevacizumab resources

• Bevacizumab Side Effects (in more detail)
• Bevacizumab Dosage
• Bevacizumab Use in Pregnancy & Breastfeeding
• Bevacizumab Drug Interactions
• Bevacizumab Support Group
• 6 Reviews for Bevacizumab - Add your own review/rating

• bevacizumab Intravenous Advanced Consumer (Micromedex) - Includes Dosage Information


• Bevacizumab Professional Patient Advice (Wolters Kluwer)


• Bevacizumab Solution MedFacts Consumer Leaflet (Wolters Kluwer)


• Bevacizumab Monograph (AHFS DI)


• Avastin Prescribing Information (FDA)


• Avastin Consumer Overview

Compare bevacizumab with other medications

• Breast Cancer
• Breast Cancer, Metastatic
• Colorectal Cancer
• Glioblastoma Multiforme
• Macular Degeneration
• Malignant Glioma
• Neurofibromatosis
• Non-Small Cell Lung Cancer
• Ovarian Cancer
• Pancreatic Cancer
• Renal Cell Carcinoma
• Solid Tumors

Where can I get more information?

• Your doctor or pharmacist can provide more information about bevacizumab.

See also: bevacizumab side effects (in more detail)

Oxacil

Oxacil may be available in the countries listed below.

Ingredient matches for Oxacil

Oxacillin

Oxacillin is reported as an ingredient of Oxacil in the following countries:

• Tunisia

International Drug Name Search

Losartan / Hydrochlorothiazide Qualimed

Losartan/Hydrochlorothiazide Qualimed may be available in the countries listed below.

Ingredient matches for Losartan/Hydrochlorothiazide Qualimed

Hydrochlorothiazide

Hydrochlorothiazide is reported as an ingredient of Losartan/Hydrochlorothiazide Qualimed in the following countries:

• France

Losartan

Losartan potassium salt (a derivative of Losartan) is reported as an ingredient of Losartan/Hydrochlorothiazide Qualimed in the following countries:

• France

International Drug Name Search

Pinamet

Pinamet may be available in the countries listed below.

Ingredient matches for Pinamet

Cimetidine

Cimetidine is reported as an ingredient of Pinamet in the following countries:

• Ireland

International Drug Name Search

Alna retard

Alna retard may be available in the countries listed below.

Ingredient matches for Alna retard

Tamsulosin

Tamsulosin hydrochloride (a derivative of Tamsulosin) is reported as an ingredient of Alna retard in the following countries:

• Austria

International Drug Name Search

Cytarabine Hydrochloride

Cytarabine Hydrochloride may be available in the countries listed below.

Ingredient matches for Cytarabine Hydrochloride

Cytarabine

Cytarabine Hydrochloride (USAN) is known as Cytarabine in the US.

International Drug Name Search

Glossary

USAN	United States Adopted Name

Click for further information on drug naming conventions and International Nonproprietary Names.

Fluxacina L.CH.

Fluxacina L.CH. may be available in the countries listed below.

Ingredient matches for Fluxacina L.CH.

Flucloxacillin

Flucloxacillin is reported as an ingredient of Fluxacina L.CH. in the following countries:

• Chile

International Drug Name Search

Tramadol-Mepha

Tramadol-Mepha may be available in the countries listed below.

Ingredient matches for Tramadol-Mepha

Tramadol

Tramadol hydrochloride (a derivative of Tramadol) is reported as an ingredient of Tramadol-Mepha in the following countries:

• Switzerland

International Drug Name Search

Deldrax

Deldrax may be available in the countries listed below.

In some countries, this medicine may only be approved for veterinary use.

Ingredient matches for Deldrax

Nitroxinil

Nitroxinil is reported as an ingredient of Deldrax in the following countries:

• Ireland

International Drug Name Search

Clotiazépam

Clotiazépam may be available in the countries listed below.

Ingredient matches for Clotiazépam

Clotiazepam

Clotiazépam (DCF) is also known as Clotiazepam (Prop.INN)

International Drug Name Search

Glossary

DCF	Dénomination Commune Française
Prop.INN	Proposed International Nonproprietary Name (World Health Organization)

Click for further information on drug naming conventions and International Nonproprietary Names.

Nystaform

Nystaform may be available in the countries listed below.

Ingredient matches for Nystaform

Chlorhexidine

Chlorhexidine dihydrochloride (a derivative of Chlorhexidine) is reported as an ingredient of Nystaform in the following countries:

• United Kingdom

Nystatin

Nystatin is reported as an ingredient of Nystaform in the following countries:

• United Kingdom

International Drug Name Search

Vitamin B1 Winthrop

Vitamin B1 Winthrop may be available in the countries listed below.

Ingredient matches for Vitamin B1 Winthrop

Thiamine

Thiamine hydrochloride (a derivative of Thiamine) is reported as an ingredient of Vitamin B1 Winthrop in the following countries:

• Germany

International Drug Name Search

Venotrulan Trox

Venotrulan Trox may be available in the countries listed below.

Ingredient matches for Venotrulan Trox

Troxerutin

Troxerutin is reported as an ingredient of Venotrulan Trox in the following countries:

• Germany

International Drug Name Search

Paroxetine ratiopharm

Paroxetine ratiopharm may be available in the countries listed below.

Ingredient matches for Paroxetine ratiopharm

Paroxetine

Paroxetine is reported as an ingredient of Paroxetine ratiopharm in the following countries:

• Belgium

Paroxetine hydrochloride (a derivative of Paroxetine) is reported as an ingredient of Paroxetine ratiopharm in the following countries:

• Czech Republic


• Luxembourg


• Netherlands

International Drug Name Search

Anatifen

Anatifen may be available in the countries listed below.

Ingredient matches for Anatifen

Ketotifen

Ketotifen fumarate (a derivative of Ketotifen) is reported as an ingredient of Anatifen in the following countries:

• Japan

International Drug Name Search

Ucol

Ucol may be available in the countries listed below.

Ingredient matches for Ucol

Tolterodine

Tolterodine tartrate (a derivative of Tolterodine) is reported as an ingredient of Ucol in the following countries:

• Bangladesh

International Drug Name Search

Negaflox

Negaflox may be available in the countries listed below.

Ingredient matches for Negaflox

Norfloxacin

Norfloxacin is reported as an ingredient of Negaflox in the following countries:

• Eritrea


• Kenya


• Myanmar


• Nigeria


• Sri Lanka


• Tanzania


• Uganda


• Zambia


• Zimbabwe

International Drug Name Search

Propyl

Propyl may be available in the countries listed below.

Ingredient matches for Propyl

Propylthiouracil

Propylthiouracil is reported as an ingredient of Propyl in the following countries:

• Singapore

International Drug Name Search

Vicks Hoestsiroop

Vicks Hoestsiroop may be available in the countries listed below.

Ingredient matches for Vicks Hoestsiroop

Dextromethorphan

Dextromethorphan hydrobromide (a derivative of Dextromethorphan) is reported as an ingredient of Vicks Hoestsiroop in the following countries:

• Netherlands

International Drug Name Search

Wellcoprim

Wellcoprim may be available in the countries listed below.

Ingredient matches for Wellcoprim

Trimethoprim

Trimethoprim is reported as an ingredient of Wellcoprim in the following countries:

• Luxembourg

International Drug Name Search

Lansoprazole ratiopharm

Lansoprazole ratiopharm may be available in the countries listed below.

Ingredient matches for Lansoprazole ratiopharm

Lansoprazole

Lansoprazole is reported as an ingredient of Lansoprazole ratiopharm in the following countries:

• France

International Drug Name Search

Grefen

Grefen may be available in the countries listed below.

Ingredient matches for Grefen

Ibuprofen

Ibuprofen is reported as an ingredient of Grefen in the following countries:

• Switzerland

International Drug Name Search

Dixamid

Dixamid may be available in the countries listed below.

Ingredient matches for Dixamid

Indapamide

Indapamide is reported as an ingredient of Dixamid in the following countries:

• Greece

International Drug Name Search

Omeprazol Domesco

Omeprazol Domesco may be available in the countries listed below.

Ingredient matches for Omeprazol Domesco

Omeprazole

Omeprazole is reported as an ingredient of Omeprazol Domesco in the following countries:

• Vietnam

International Drug Name Search

Fertinorm P

Fertinorm P may be available in the countries listed below.

Ingredient matches for Fertinorm P

Menotropins

Menotropins is reported as an ingredient of Fertinorm P in the following countries:

• Japan

International Drug Name Search

Buflomédil Zydus

Buflomédil Zydus may be available in the countries listed below.

Ingredient matches for Buflomédil Zydus

Buflomedil

Buflomedil hydrochloride (a derivative of Buflomedil) is reported as an ingredient of Buflomédil Zydus in the following countries:

• France

International Drug Name Search

Metabolin G

Metabolin G may be available in the countries listed below.

Ingredient matches for Metabolin G

Thiamine

Thiamine hydrochloride (a derivative of Thiamine) is reported as an ingredient of Metabolin G in the following countries:

• Japan

International Drug Name Search

Paroxetina Pharmakern

Paroxetina Pharmakern may be available in the countries listed below.

Ingredient matches for Paroxetina Pharmakern

Paroxetine

Paroxetine hydrochloride (a derivative of Paroxetine) is reported as an ingredient of Paroxetina Pharmakern in the following countries:

• Portugal

International Drug Name Search

Dr. Scholl's Cushlin Ultra Slim Corn Removers Topical

Generic Name: salicylic acid (Topical route)

sal-i-SIL-ik AS-id

Commonly used brand name(s)

In the U.S.

• Akurza


• Aliclen


• Avosil


• Betasal


• Compound W


• Corn Removing


• Dermarest Psoriasis


• DHS Sal


• Drytex


• Duofilm


• Duoplant


• Durasal


• Freezone


• Fung-O


• Gets-It Corn/Callus Remover


• Gordofilm


• Hydrisalic


• Ionil


• Ionil Plus


• Keralyt


• Keralyt Scalp


• Lupicare


• Mediplast


• Mg217 Sal-Acid


• Mosco Corn & Callus Remover


• Neutrogena


• Occlusal-HP


• Off-Ezy


• Oxy Balance


• P & S


• Palmer's Skin Success Acne Cleanser


• Propa pH


• Salac


• Sal-Acid Plaster


• Salactic Film


• Salex


• Salitop


• Salkera


• Sal-Plant Gel


• Salvax


• Seba-Clear


• Stri-Dex


• Thera-Sal


• Therasoft Anti-Acne


• Tinamed


• Ti-Seb


• Virasal


• Wart-Off Maximum Strength


• Zapzyt

In Canada

• Acnex


• Acnomel Acne Mask


• Clear Away Wart Removal System


• Compound W One-Step Wart Remover


• Compound W Plus


• Dr. Scholl's Clear Away One Step Plantar Wart Remover


• Dr. Scholl's Cushlin Ultra Slim Callus Removers


• Dr. Scholl's Cushlin Ultra Slim Corn Removers


• Duoforte 27


• Freezone - One Step Callus Remover Pad


• Freezone - One Step Corn Remover Pad

Available Dosage Forms:

• Soap


• Lotion


• Liquid


• Foam


• Ointment


• Gel/Jelly


• Solution


• Cream


• Pad


• Paste


• Shampoo


• Dressing


• Stick

Therapeutic Class: Antiacne

Pharmacologic Class: NSAID

Chemical Class: Salicylate, Non-Aspirin

Uses For Dr. Scholl's Cushlin Ultra Slim Corn Removers

Salicylic acid is used to treat many skin disorders, such as acne, dandruff, psoriasis, seborrheic dermatitis of the skin and scalp, calluses, corns, common warts, and plantar warts, depending on the dosage form and strength of the preparation.

Some of these preparations are available only with your doctor's prescription.

Before Using Dr. Scholl's Cushlin Ultra Slim Corn Removers

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Young children may be at increased risk of unwanted effects because of increased absorption of salicylic acid through the skin. Also, young children may be more likely to get skin irritation from salicylic acid. Salicylic acid should not be applied to large areas of the body, used for long periods of time, or used under occlusive dressing (air-tight covering, such as kitchen plastic wrap) in infants and children. Salicylic acid should not be used in children younger than 2 years of age.

Geriatric

Elderly people are more likely to have age-related blood vessel disease. This may increase the chance of problems during treatment with this medicine.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Abciximab


• Argatroban


• Bivalirudin


• Cilostazol


• Citalopram


• Clovoxamine


• Dabigatran Etexilate


• Dipyridamole


• Escitalopram


• Femoxetine


• Flesinoxan


• Fluoxetine


• Fluvoxamine


• Fondaparinux


• Heparin


• Lepirudin


• Nefazodone


• Paroxetine


• Protein C


• Rivaroxaban


• Sertraline


• Sibutramine


• Ticlopidine


• Tirofiban


• Vilazodone


• Zimeldine

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Acenocoumarol


• Anisindione


• Ardeparin


• Azilsartan Medoxomil


• Azosemide


• Bemetizide


• Bendroflumethiazide


• Benzthiazide


• Bumetanide


• Buthiazide


• Candesartan Cilexetil


• Certoparin


• Chlorothiazide


• Chlorthalidone


• Clopamide


• Cyclopenthiazide


• Dalteparin


• Danaparoid


• Dicumarol


• Enoxaparin


• Eprosartan


• Ethacrynic Acid


• Furosemide


• Hydrochlorothiazide


• Hydroflumethiazide


• Indapamide


• Irbesartan


• Losartan


• Methyclothiazide


• Metolazone


• Nadroparin


• Olmesartan Medoxomil


• Parnaparin


• Phenindione


• Phenprocoumon


• Piretanide


• Polythiazide


• Probenecid


• Reviparin


• Tamarind


• Tasosartan


• Telmisartan


• Tinzaparin


• Torsemide


• Trichlormethiazide


• Valsartan


• Warfarin


• Xipamide

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Blood vessel disease

• Diabetes mellitus (sugar diabetes)—Use of this medicine may cause severe redness or ulceration, especially on the hands or feet

• Inflammation, irritation, or infection of the skin—Use of this medicine may cause severe irritation if applied to inflamed, irritated, or infected area of the skin

• Influenza (flu) or


• Varicella (chicken pox)—This medicine should not be used in children and teenagers with the flu or chicken pox. There is a risk of Reye's syndrome.

• Kidney disease or


• Liver disease—Using this medicine for a long time over large areas could result in unwanted effects

Proper Use of salicylic acid

This section provides information on the proper use of a number of products that contain salicylic acid. It may not be specific to Dr. Scholl's Cushlin Ultra Slim Corn Removers. Please read with care.

It is very important that you use this medicine only as directed. Do not use more of it, do not use it more often, and do not use it for a longer time than recommended on the label, unless otherwise directed by your doctor. To do so may increase the chance of absorption through the skin and the chance of salicylic acid poisoning.

If your doctor has ordered an occlusive dressing (airtight covering, such as kitchen plastic wrap) to be applied over this medicine, make sure you know how to apply it. Since an occlusive dressing will increase the amount of medicine absorbed through your skin and the possibility of salicylic acid poisoning, use it only as directed. If you have any questions about this, check with your doctor.

Keep this medicine away from the eyes and other mucous membranes, such as the mouth and inside of the nose. If you should accidentally get some in your eyes or on other mucous membranes, immediately flush them with water for 15 minutes.

To use the cream, lotion, or ointment form of salicylic acid:

• Apply enough medicine to cover the affected area, and rub in gently.

To use the gel form of salicylic acid:

• Before using salicylic acid gel, apply wet packs to the affected areas for at least 5 minutes. If you have any questions about this, check with your health care professional.


• Apply enough gel to cover the affected areas, and rub in gently.

To use the pad form of salicylic acid:

• Wipe the pad over the affected areas.


• Do not rinse off medicine after treatment.

To use the plaster form of salicylic acid for warts, corns, or calluses:

• This medicine comes with patient instructions. Read them carefully before using.


• Do not use this medicine on irritated skin or on any area that is infected or reddened. Also, do not use this medicine if you are a diabetic or if you have poor blood circulation.


• Do not use this medicine on warts with hair growing from them or on warts on the face, in or on the genital (sex) organs, or inside the nose or mouth. Also do not use on moles or birthmarks. To do so may cause severe irritation.


• Wash the area to be treated and dry thoroughly. Warts may be soaked in warm water for 5 minutes before drying.


• Cut the plaster to fit the wart, corn, or callus and apply.


• For corns and calluses:
  
  • Repeat every 48 hours as needed for up to 14 days, or as directed by your doctor, until the corn or callus is removed.
  
  
  • Corns or calluses may be soaked in warm water for 5 minutes to help in their removal.
  
  


• For warts:
  
  • Depending on the product, either:
    
    • Apply plaster and repeat every 48 hours as needed, or
      
      • Apply plaster at bedtime, leave in place for at least 8 hours, remove plaster in the morning, and repeat every 24 hours as needed.
      
      
    
    
  
  
  • Repeat for up to 12 weeks as needed, or as directed by your doctor, until wart is removed.
  
  


• If discomfort gets worse during treatment or continues after treatment, or if the wart spreads, check with your doctor.

To use the shampoo form of salicylic acid:

• Before applying this medicine, wet the hair and scalp with lukewarm water. Apply enough medicine to work up a lather and rub well into the scalp for 2 or 3 minutes, then rinse. Apply the medicine again and rinse thoroughly.

To use the soap form of salicylic acid:

• Work up a lather with the soap, using hot water, and scrub the entire affected area with a washcloth or facial sponge or mitt.


• If you are to use this soap in a foot bath, work up rich suds in hot water and soak the feet for 10 to 15 minutes. Then pat dry without rinsing.

To use the topical solution form of salicylic acid for acne:

• Wet a cotton ball or pad with the topical solution and wipe the affected areas.


• Do not rinse off medicine after treatment.

To use the topical solution form of salicylic acid for warts, corns, or calluses:

• This medicine comes with patient instructions. Read them carefully before using.


• This medicine is flammable. Do not use it near heat or open flame or while smoking.


• Do not use this medicine on irritated skin or on any area that is infected or reddened. Also, do not use this medicine if you are a diabetic or if you have poor blood circulation.


• Do not use this medicine on warts with hair growing from them or on warts on the face, in or on the genital (sex) organs, or inside the nose or mouth. Also do not use on moles or birthmarks. To do so may cause severe irritation.


• Avoid breathing in the vapors from the medicine.


• Wash the area to be treated and dry thoroughly. Warts may be soaked in warm water for 5 minutes before drying.


• Apply the medicine one drop at a time to completely cover each wart, corn, or callus. Let dry.


• For warts—Repeat one or two times a day as needed for up to 12 weeks, or as directed by your doctor, until wart is removed.


• For corns and calluses—Repeat one or two times a day as needed for up to 14 days, or as directed by your doctor, until the corn or callus is removed.


• Corns and calluses may be soaked in warm water for 5 minutes to help in their removal.


• If discomfort gets worse during treatment or continues after treatment, or if the wart spreads, check with your doctor.

Unless your hands are being treated, wash them immediately after applying this medicine to remove any medicine that may be on them.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For cream dosage form:
  
  • For corns and calluses:
    
    • Adults and children—Use the 2 to 10% cream as needed. Use the 25 to 60% cream one time every three to five days.
    
    
  
  


• For gel dosage form:
  
  • For acne:
    
    • Adults and children—Use the 0.5 to 5% gel one time a day.
    
    
  
  
  • For psoriasis:
    
    • Adults and children—Use the 5% gel one time a day.
    
    
  
  
  • For common warts:
    
    • Adults and children—Use the 5 to 26% gel one time a day.
    
    
  
  


• For lotion dosage form:
  
  • For acne:
    
    • Adults and children—Use the 1 to 2% lotion one to three times a day.
    
    
  
  
  • For dandruff and antiseborrhic dermatitis of the scalp:
    
    • Adults and children—Use the 1.8 to 2% lotion on the scalp one or two times a day.
    
    
  
  


• For ointment dosage form:
  
  • For acne:
    
    • Adults and children—Use the 3 to 6% ointment as needed.
    
    
  
  
  • For psoriasis and seborrheic dermatitis:
    
    • Adults and children—Use the 3 to 10% ointment as needed.
    
    
  
  
  • For common warts:
    
    • Adults and children—Use the 3 to 10% ointment as needed. Use the 25 to 60% ointment one time every three to five days.
    
    
  
  


• For pads dosage form:
  
  • For acne:
    
    • Adults and children—Use one to three times a day.
    
    
  
  


• For plaster dosage form:
  
  • For corns, calluses, common warts, or plantar warts:
    
    • Adults and children—Use one time a day or one time every other day.
    
    
  
  


• For shampoo dosage form:
  
  • For dandruff or seborrheic dermatitis of the scalp:
    
    • Adults and children—Use on the scalp one or two times a week.
    
    
  
  


• For soap dosage form:
  
  • For acne:
    
    • Adults and children—Use as needed.
    
    
  
  


• For topical solution dosage form:
  
  • For acne:
    
    • Adults and children—Use the 0.5 to 2% topical solution one to three times a day.
    
    
  
  
  • For common warts and plantar warts:
    
    • Adults and children—Use the 5 to 27% topical solution one or two times a day.
    
    
  
  
  • For corns and calluses:
    
    • Adults and children—Use the 12 to 27% topical solution one or two times a day.
    
    
  
  

Missed Dose

If you miss a dose of this medicine, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Precautions While Using Dr. Scholl's Cushlin Ultra Slim Corn Removers

When using salicylic acid, do not use any of the following preparations on the same affected area as this medicine, unless otherwise directed by your doctor:

• Abrasive soaps or cleansers


• Alcohol-containing preparations


• Any other topical acne preparation or preparation containing a peeling agent (for example, benzoyl peroxide, resorcinol, sulfur, or tretinoin [vitamin A acid])


• Cosmetics or soaps that dry the skin


• Medicated cosmetics


• Other topical medicine for the skin

To use any of the above preparations on the same affected area as salicylic acid may cause severe irritation of the skin.

Check with your doctor right away if you have nausea, vomiting, dizziness, loss of hearing, tinnitus, lethargy hyperpnea, diarrhea, and psychic disturbances. These could be symptoms of a serious condition called salicylate toxicity, especially in children under 12 years of age and patients with kidney or liver problems.

Dr. Scholl's Cushlin Ultra Slim Corn Removers Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

Less common or rare

• Skin irritation not present before use of this medicine (moderate or severe)

Frequency not known

• Dryness and peeling of skin


• flushing


• redness of skin


• unusually warm skin

Symptoms of salicylic acid poisoning

• Confusion


• diarrhea


• dizziness


• fast or deep breathing


• headache (severe or continuing)


• hearing loss


• lightheadedness


• nausea


• rapid breathing


• ringing or buzzing in ears (continuing)


• severe drowsiness


• stomach pain


• vomiting

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

• Skin irritation not present before use of this medicine (mild)


• stinging

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Dr. Scholl's Cushlin Ultra Slim Corn Removers Topical side effects (in more detail)

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More Dr. Scholl's Cushlin Ultra Slim Corn Removers Topical resources

• Dr. Scholl's Cushlin Ultra Slim Corn Removers Topical Side Effects (in more detail)
• Dr. Scholl's Cushlin Ultra Slim Corn Removers Topical Use in Pregnancy & Breastfeeding
• Dr. Scholl's Cushlin Ultra Slim Corn Removers Topical Drug Interactions
• Dr. Scholl's Cushlin Ultra Slim Corn Removers Topical Support Group
• 1 Review for Dr. Scholl's Cushlin Ultra Slim Corn Removers Topical - Add your own review/rating

Compare Dr. Scholl's Cushlin Ultra Slim Corn Removers Topical with other medications

• Acne
• Dermatological Disorders
• Warts

Canifug Cremolum

Canifug Cremolum may be available in the countries listed below.

Ingredient matches for Canifug Cremolum

Clotrimazole

Clotrimazole is reported as an ingredient of Canifug Cremolum in the following countries:

• Germany

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Lamisil

In some countries, this medicine may only be approved for veterinary use.

In the US, Lamisil (terbinafine systemic) is a member of the drug class miscellaneous antifungals and is used to treat Cutaneous Candidiasis, Onychomycosis - Fingernail, Onychomycosis - Toenail, Tinea Capitis, Tinea Corporis, Tinea Cruris and Tinea Pedis.

US matches:

• Lamisil


• Lamisil AT Cream


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• Lamisil AT Athletes Foot


• Lamisil AT Jock Itch


• Lamisil Topical


• Lamisil AT Topical


• Lamisil Dermgel Topical


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• Lamisil AT for Women

UK matches:

• Lamisil Tablets 250mg
• Lamisil AT 1% Cream (SPC)
• Lamisil AT 1% Gel (SPC)
• Lamisil AT 1% Spray (SPC)
• Lamisil Cream (SPC)
• Lamisil Once (SPC)

Ingredient matches for Lamisil

Terbinafine

Terbinafine is reported as an ingredient of Lamisil in the following countries:

• Algeria


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• Colombia


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Terbinafine hydrochloride (a derivative of Terbinafine) is reported as an ingredient of Lamisil in the following countries:

• Algeria


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• Australia


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• Belgium


• Benin


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Glossary

SPC	Summary of Product Characteristics (UK)

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Carboplatin Gerolymatos

Carboplatin Gerolymatos may be available in the countries listed below.

Ingredient matches for Carboplatin Gerolymatos

Carboplatin

Carboplatin is reported as an ingredient of Carboplatin Gerolymatos in the following countries:

• Greece

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Claritromicina Cuve

Claritromicina Cuve may be available in the countries listed below.

Ingredient matches for Claritromicina Cuve

Clarithromycin

Clarithromycin is reported as an ingredient of Claritromicina Cuve in the following countries:

• Spain

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Enalapril axcount

Enalapril axcount may be available in the countries listed below.

Ingredient matches for Enalapril axcount

Enalapril

Enalapril maleate (a derivative of Enalapril) is reported as an ingredient of Enalapril axcount in the following countries:

• Germany

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Dacogen

Generic Name: decitabine (de SIT a been)

Brand Names: Dacogen

What is decitabine?

Decitabine is a cancer medication that interferes with the growth and spread of cancer cells in the body.

Decitabine is used to treat myelodysplastic syndromes (certain types of blood or bone marrow cancer).

Decitabine may also be used for purposes not listed in this medication guide.

What is the most important information I should know about decitabine?

Before receiving this medication, tell your doctor if you have liver or kidney disease.

Do not use decitabine if you are pregnant. It could harm the unborn baby. Use effective birth control, and tell your doctor if you become pregnant during treatment. If a man fathers a child while using this medication, the baby may have birth defects. Use a condom to prevent pregnancy during your treatment. Continue using condoms for at least 2 months after you stop receiving decitabine. You should not breast-feed while you are receiving decitabine.

Decitabine can lower blood cells that help your body fight infections. Avoid being near people who are sick or have infections. Avoid activities that may increase your risk of bleeding or injury. Your blood may need to be tested often. Visit your doctor regularly.

What should I discuss with my health care provider before receiving decitabine?

To make sure you can safely take decitabine, tell your doctor if you have any of these other conditions:

• 
  

  kidney disease; or

  
  


• 
  

  liver disease.

  
  

FDA pregnancy category D. Do not use decitabine if you are pregnant. It could harm the unborn baby. Use effective birth control, and tell your doctor if you become pregnant during treatment. If a man fathers a child while using this medication, the baby may have birth defects. Use a condom to prevent pregnancy during your treatment. Continue using condoms for at least 2 months after you stop receiving decitabine. It is not known whether decitabine passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are receiving decitabine.

How is decitabine given?

Decitabine is injected into a vein through an IV. You will receive this injection in a clinic or hospital setting. Decitabine must be given slowly, and the IV infusion can take up to 3 hours to complete.

In most cases, a decitabine injection is given every 8 hours for 3 days. This 3-day treatment is usually repeated every 6 weeks. You will most likely receive at least 4 of these treatments.

You may be given other medications to prevent nausea or vomiting while you are receiving decitabine.

Decitabine can lower blood cells that help your body fight infections. This can make it easier for you to bleed from an injury or get sick from being around others who are ill. Your blood may need to be tested often. Your kidney or liver function may also need to be tested. Visit your doctor regularly.

What happens if I miss a dose?

Call your doctor for instructions if you miss an appointment for your decitabine injection.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include some of the serious side effects listed in this medication guide.

What should I avoid while receiving decitabine?

Avoid being near people who are sick or have infections. Tell your doctor at once if you develop signs of infection.

Avoid activities that may increase your risk of bleeding or injury. Use extra care to prevent bleeding while shaving or brushing your teeth.

Decitabine side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have a serious side effect such as:

• 
  

  fever, chills, body aches, cough, sore throat, flu symptoms;

  
  


• 
  

  easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin;

  
  


• 
  

  pale skin, feeling light-headed or short of breath, rapid heart rate, trouble concentrating;

  
  


• 
  

  white patches or sores inside your mouth or on your lips; or

  
  


• 
  

  stabbing chest pain, wheezing, feeling short of breath, cough with yellow or green mucus;

  
  


• 
  

  swelling, pain, tenderness, or redness anywhere on your body; or

  
  


• 
  

  electrolyte imbalance (confusion, uneven heart rate, extreme thirst, increased urination, jerking muscle movements, leg discomfort, muscle weakness or limp feeling).

  
  

Less serious side effects may include:

• 
  

  headache, dizziness;

  
  


• 
  

  tired feeling;

  
  


• 
  

  nausea, vomiting, stomach pain, diarrhea, constipation;

  
  


• 
  

  cough;

  
  


• 
  

  increased thirst, increased urination, hunger, dry mouth, drowsiness;

  
  


• 
  

  joint pain; or

  
  


• 
  

  sleep problems (insomnia).

  
  

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect decitabine?

There may be other drugs that can interact with decitabine. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

More Dacogen resources

• Dacogen Side Effects (in more detail)
• Dacogen Use in Pregnancy & Breastfeeding
• Dacogen Drug Interactions
• Dacogen Support Group
• 0 Reviews for Dacogen - Add your own review/rating

• Dacogen Prescribing Information (FDA)


• Dacogen Monograph (AHFS DI)


• Dacogen Advanced Consumer (Micromedex) - Includes Dosage Information


• Dacogen Consumer Overview


• Dacogen MedFacts Consumer Leaflet (Wolters Kluwer)


• Decitabine Professional Patient Advice (Wolters Kluwer)

Compare Dacogen with other medications

• Myelodysplastic Syndrome

Where can I get more information?

• Your doctor or pharmacist can provide more information about decitabine.

See also: Dacogen side effects (in more detail)

Basteen

Basteen may be available in the countries listed below.

Ingredient matches for Basteen

Norfloxacin

Norfloxacin is reported as an ingredient of Basteen in the following countries:

• Japan

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Serevent Rotadisk

Serevent Rotadisk may be available in the countries listed below.

Ingredient matches for Serevent Rotadisk

Salmeterol

Salmeterol xinafoate (a derivative of Salmeterol) is reported as an ingredient of Serevent Rotadisk in the following countries:

• Austria

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Primogyna

Primogyna may be available in the countries listed below.

Ingredient matches for Primogyna

Estradiol

Estradiol 17ß-valerate (a derivative of Estradiol) is reported as an ingredient of Primogyna in the following countries:

• Brazil

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Natrijev hidrogenkarbonat

Natrijev hidrogenkarbonat may be available in the countries listed below.

Ingredient matches for Natrijev hidrogenkarbonat

Sodium Bicarbonate

Sodium Bicarbonate is reported as an ingredient of Natrijev hidrogenkarbonat in the following countries:

• Slovenia

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Clorpromazina Duncan

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Chlorpromazine

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• Argentina

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Vibranord

Vibranord may be available in the countries listed below.

Ingredient matches for Vibranord

Doxycycline

Doxycycline hyclate (a derivative of Doxycycline) is reported as an ingredient of Vibranord in the following countries:

• Sweden

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Oxitocina

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Oxytocin

Oxitocina (DCIT) is known as Oxytocin in the US.

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DCIT	Denominazione Comune Italiana

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Prednisol

In some countries, this medicine may only be approved for veterinary use.

In the US, Prednisol (prednisolone ophthalmic) is a member of the drug class ophthalmic steroids and is used to treat Postoperative Ocular Inflammation.

US matches:

• Prednisol

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Prednisolone

Prednisolone 21-acetate (a derivative of Prednisolone) is reported as an ingredient of Prednisol in the following countries:

• Netherlands

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Ciprofloxacine Apotex

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Ciprofloxacin

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Flavost

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Ipriflavone

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Oxifungol

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Fluconazole

Fluconazole is reported as an ingredient of Oxifungol in the following countries:

• Mexico

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Rosazol

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Metronidazole

Metronidazole is reported as an ingredient of Rosazol in the following countries:

• Finland

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Prazosina

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Prazosin

Prazosin is reported as an ingredient of Prazosina in the following countries:

• Colombia

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Predxal

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Telmisartan

Telmisartan is reported as an ingredient of Predxal in the following countries:

• Mexico

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Gestoden / Ethinylestradiol 75 / 30 Schering

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Riomet

Generic Name: metformin (Oral route)

met-FOR-min hye-droe-KLOR-ide

Oral route(Tablet;Tablet, Extended Release;Solution)

Fortamet(R), Glucophage(R), Glucophage XR(R), Riomet(R): Lactic acidosis is a rare, but serious, metabolic complication that can occur due to metformin accumulation during treatment with metformin hydrochloride; when it occurs, it is fatal in approximately 50% of cases. Lactic acidosis may also occur in association with pathophysiologic conditions, including diabetes mellitus, characterized by significant tissue hypoperfusion and hypoxemia. The risk of lactic acidosis increases with renal impairment, increased age, congestive heart failure, and hepatic insufficiency. Treatment with metformin should not be initiated in patients 80 years old or older, unless measurement of creatinine clearance demonstrates that renal function is normal. Therapy should temporarily be discontinued prior to any intravascular radiocontrast study or surgical procedure. Excessive alcohol use should be avoided, because alcohol potentiates the effects of metformin on lactate metabolism. Discontinue therapy immediately and institute supportive measures promptly for suspected lactic acidosis .

Oral route(Tablet, Extended Release)

Glumetza(R): Lactic acidosis is a rare, but serious, complication that can occur due to metformin accumulation. The risk of lactic acidosis increases with renal or hepatic impairment, acute congestive heart failure, sepsis, dehydration, and excess alcohol intake. Onset may be subtle and include nonspecific symptoms such as malaise, myalgia, respiratory distress, somnolence, and abdominal distress; laboratory abnormalities include low pH, increased anion gap and elevated blood lactate. If lactic acidosis is suspected, Glumetza(R) should be discontinued and the patient immediately hospitalized .

Commonly used brand name(s)

In the U.S.

• Fortamet


• Glucophage


• Glucophage XR


• Glumetza


• Riomet

Available Dosage Forms:

• Tablet


• Tablet, Extended Release


• Solution

Therapeutic Class: Hypoglycemic

Chemical Class: Metformin

Uses For Riomet

Metformin is used to treat high blood sugar levels that are caused by a type of diabetes mellitus or sugar diabetes called type 2 diabetes. With this type of diabetes, insulin produced by the pancreas is not able to get sugar into the cells of the body where it can work properly. Using metformin alone, with a type of oral antidiabetic medicine called a sulfonylurea, or with insulin, will help to lower blood sugar when it is too high and help restore the way you use food to make energy.

Many people can control type 2 diabetes with diet and exercise. Following a specially planned diet and exercise will always be important when you have diabetes, even when you are taking medicines. To work properly, the amount of metformin you take must be balanced against the amount and type of food you eat and the amount of exercise you do. If you change your diet or exercise, you will want to test your blood sugar to find out if it is too low. Your doctor will teach you what to do if this happens.

Metformin does not help patients does not help patients who have insulin-dependent or type 1 diabetes because they cannot produce insulin from their pancreas gland. Their blood glucose is best controlled by insulin injections.

This medicine is available only with your doctor's prescription.

Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although this use is not included in product labeling, metformin is used in certain patients with the following medical conditions:

• Polycystic ovary syndrome.

Before Using Riomet

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of metformin oral solution and tablets in children 10 to 16 years of age. However, safety and efficacy of metformin extended-release tablets in the pediatric population have not been established.

Geriatric

Although appropriate studies on the relationship of age to the effects of metformin have not been performed in the geriatric population, geriatric-specific problems are not expected to limit the usefulness of metformin in the elderly. However, elderly patients are more likely to have age-related kidney problems, which may require caution in patients receiving metformin. This medicine is not recommended in patients 80 years of age and older who have kidney problems.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	B	Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate studies in pregnant women OR animal studies have shown an adverse effect, but adequate studies in pregnant women have failed to demonstrate a risk to the fetus.

Breast Feeding

Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

• Acetrizoic Acid


• Diatrizoate


• Ethiodized Oil


• Iobenzamic Acid


• Iobitridol


• Iocarmic Acid


• Iocetamic Acid


• Iodamide


• Iodipamide


• Iodixanol


• Iodohippuric Acid


• Iodopyracet


• Iodoxamic Acid


• Ioglicic Acid


• Ioglycamic Acid


• Iohexol


• Iomeprol


• Iopamidol


• Iopanoic Acid


• Iopentol


• Iophendylate


• Iopromide


• Iopronic Acid


• Ioseric Acid


• Iosimide


• Iotasul


• Iothalamate


• Iotrolan


• Iotroxic Acid


• Ioversol


• Ioxaglate


• Ioxitalamic Acid


• Ipodate


• Metrizamide


• Metrizoic Acid


• Tyropanoate Sodium

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Acetazolamide


• Alatrofloxacin


• Balofloxacin


• Cimetidine


• Ciprofloxacin


• Clinafloxacin


• Dichlorphenamide


• Dofetilide


• Enoxacin


• Fleroxacin


• Flumequine


• Gatifloxacin


• Gemifloxacin


• Grepafloxacin


• Levofloxacin


• Lomefloxacin


• Moxifloxacin


• Norfloxacin


• Ofloxacin


• Pefloxacin


• Prulifloxacin


• Rufloxacin


• Sparfloxacin


• Temafloxacin


• Topiramate


• Tosufloxacin


• Trovafloxacin Mesylate


• Zonisamide

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Acebutolol


• Alprenolol


• Atenolol


• Betaxolol


• Bevantolol


• Bisoprolol


• Bitter Melon


• Bucindolol


• Carteolol


• Carvedilol


• Celiprolol


• Cephalexin


• Clorgyline


• Dilevalol


• Enalaprilat


• Enalapril Maleate


• Esmolol


• Fenugreek


• Glucomannan


• Guar Gum


• Iproniazid


• Isocarboxazid


• Labetalol


• Levobunolol


• Mepindolol


• Metipranolol


• Metoprolol


• Moclobemide


• Nadolol


• Nebivolol


• Nialamide


• Oxprenolol


• Pargyline


• Penbutolol


• Phenelzine


• Pindolol


• Procarbazine


• Propranolol


• Psyllium


• Rifampin


• Selegiline


• Sotalol


• Talinolol


• Tertatolol


• Timolol


• Toloxatone


• Tranylcypromine


• Trospium

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Alcohol, excessive use or


• Underactive adrenal glands or


• Underactive pituitary gland or


• Undernourished condition or


• Weakened physical condition or


• Any other condition that causes low blood sugar—Patients with these conditions may be more likely to develop low blood sugar while taking metformin.

• Anemia (low levels of red blood cells) or


• Vitamin B12 deficiency—Use with caution. May make these conditions worse.

• Congestive heart failure, acute or unstable or


• Dehydration or


• Heart attack, acute or


• Hypoxemia (decreased oxygen in the blood) or


• Kidney disease or


• Liver disease or


• Sepsis (blood poisoning) or


• Shock (low blood pressure, blood circulation is poor)—A rare condition called lactic acidosis can occur. Talk with your doctor if you have concerns about this.

• Diabetic ketoacidosis (ketones in the blood) or


• Kidney disease, severe or


• Metabolic acidosis (extra acids in the blood) or


• Type 1 diabetes—Should not be used in patients with these conditions.

• Fever or


• Infection or


• Surgery or


• Trauma—These conditions may cause temporary problems with blood sugar control and your doctor may want to treat you with insulin.

Proper Use of metformin

This section provides information on the proper use of a number of products that contain metformin. It may not be specific to Riomet. Please read with care.

This medicine usually comes with a patient information insert. Read the information carefully and make sure you understand it before taking this medicine. If you have any questions, ask your doctor.

Carefully follow the special meal plan your doctor gave you. This is a very important part of controlling your condition, and is necessary if the medicine is to work properly. Also, exercise regularly and test for sugar in your blood or urine as directed.

Metformin should be taken with meals to help reduce stomach or bowel side effects that may occur during the first few weeks of treatment.

Swallow the extended-release tablet whole with a full glass of water. Do not crush, break, or chew it.

While taking the extended-release tablet, part of the tablet may pass into your stool after your body has absorbed the medicine. This is normal and nothing to worry about.

Measure the oral liquid with a marked measuring spoon, oral syringe, or medicine cup. The average household teaspoon may not hold the right amount of liquid.

Use only the brand of this medicine that your doctor prescribed. Different brands may not work the same way.

You may notice improvement in your blood glucose control in 1 to 2 weeks, but the full effect of blood glucose control may take up to 2 to 3 months. Ask your doctor if you have any questions about this.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For type 2 diabetes:
  
  • For oral dosage form (extended-release tablets):
    
    • Adults—
      
      • Metformin alone (Fortamet®): At first, 1000 milligrams (mg) once a day taken with the evening meal. Your doctor may increase your dose if needed until your blood sugar is controlled. However, the dose is usually not more than 2500 mg per day.
      
      
      • Metformin alone (Glucophage® XR): At first, 500 mg once daily with the evening meal. Your doctor may increase your dose if needed until your blood sugar is controlled. However, the dose is usually not more than 2000 mg per day.
      
      
      • Metformin alone (Glumetza®): At first, 500 mg once a day taken with the evening meal. Then, your doctor may increase your dose if needed until your blood sugar is controlled. However, the dose is usually not more than 2000 mg per day.
      
      
      • Metformin with a sulfonylurea: Your doctor will determine the dose of each medicine.
      
      
      • Metformin with insulin: At first, 500 mg once a day. Then, your doctor may increase your dose by 500 mg every week if needed until your blood sugar is controlled. However, the dose is usually not more than 2500 mg per day.
      
      
    
    
    • Children—Use and dose must be determined by your doctor.
    
    
  
  
  • For oral dosage form (solution):
    
    • Adults—
      
      • Metformin alone: At first, 5 milliliters (mL) two times a day, or 8.5 mL once a day with meals. Your doctor may increase your dose if needed until your blood sugar is controlled. However, the dose is usually not more than 25.5 mL per day.
      
      
      • Metformin with a sulfonylurea: Your doctor will determine the dose of each medicine.
      
      
      • Metformin with insulin: At first, 5 mL once a day. Your doctor may increase your dose if needed until your blood sugar is controlled. However, the dose is usually not more than 25 mL per day.
      
      
    
    
    • Children 10 to 16 years of age—At first, 5 mL two times a day with meals. Your doctor may increase your dose if needed until your blood sugar is controlled. However, the dose is usually not more than 20 mL per day.
    
    
    • Children younger than 10 years of age—Use and dose must be determined by your doctor.
    
    
  
  
  • For oral dosage form (tablets):
    
    • Adults—
      
      • Metformin alone: At first, 500 milligrams (mg) two times a day taken with the morning and evening meals, or 850 mg a day taken with the morning meal. Your doctor may increase your dose if needed until your blood sugar is controlled. Later, your doctor may want you to take 500 or 850 mg two to three times a day with meals. However, the dose is usually not more than 2550 mg per day.
      
      
      • Metformin with a sulfonylurea: Your doctor will determine the dose of each medicine.
      
      
      • Metformin with insulin: At first, 500 mg a day. Your doctor may increase your dose by 500 mg every week if needed until your blood sugar is controlled. However, the dose is usually not more than 2500 mg per day.
      
      
    
    
    • Children 10 to 16 years of age—At first, 500 mg two times a day taken with the morning and evening meals. Your doctor may increase your dose if needed until your blood sugar is controlled. However, the dose is usually not more than 2000 mg per day.
    
    
    • Children younger than 10 years of age—Use and dose must be determined by your doctor.
    
    
  
  

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Precautions While Using Riomet

It is very important that your doctor check your progress at regular visits, especially during the first few weeks that you take this medicine. Blood and urine tests may be needed to check for unwanted effects.

This medicine may interact with the dye used for an X-ray or CT scan. Your doctor should advise you to stop taking it before you have any medical exams or diagnostic tests that might cause less urine output than usual. You may be advised to start taking the medicine again 48 hours after the exams or tests if your kidney function is tested and found to be normal.

Make sure any doctor or dentist who treats you knows that you are using this medicine. You may need to stop using this medicine several days before having surgery or medical tests.

It is very important to carefully follow any instructions from your health care team about:

• Alcohol—Drinking alcohol may cause severe low blood sugar. Discuss this with your health care team.


• Other medicines—Do not take other medicines unless they have been discussed with your doctor. This especially includes nonprescription medicines such as aspirin, and medicines for appetite control, asthma, colds, cough, hay fever, or sinus problems.


• Counseling—Other family members need to learn how to prevent side effects or help with side effects if they occur. Also, patients with diabetes may need special counseling about diabetes medicine dosing changes that might occur with lifestyle changes, such as changes in exercise or diet. Counseling on birth control and pregnancy may be needed because of the problems that can occur in pregnancy for patients with diabetes.


• Travel—Keep a recent prescription and your medical history with you. Be prepared for an emergency as you would normally. Make allowances for changing time zones and keep your meal times as close as possible to your usual meal times.


• In case of emergency—There may be a time when you need emergency help for a problem caused by your diabetes. You need to be prepared for these emergencies. It is a good idea to wear a medical identification (ID) bracelet or neck chain at all times. Also, carry an ID card in your wallet or purse that says that you have diabetes and a list of all of your medicines.

Under certain conditions, too much metformin can cause lactic acidosis. The symptoms of lactic acidosis are severe and quick to appear, and usually occur when other health problems not related to the medicine are present and are very severe, such as a heart attack or kidney failure. Symptoms of lactic acidosis include abdominal or stomach discomfort, decreased appetite; diarrhea; fast or shallow breathing; a general feeling of discomfort; severe muscle pain or cramping; and unusual sleepiness, tiredness, or weakness.

If symptoms of lactic acidosis occur, you should get immediate emergency medical help.

Metformin can cause low blood sugar (hypoglycemia). However, this can also occur if you delay or miss a meal or snack, drink alcohol, exercise more than usual, cannot eat because of nausea or vomiting, take certain medicines, or take metformin with another type of diabetes medicine. The symptoms of low blood sugar must be treated before they lead to unconsciousness (passing out). Different people feel different symptoms of low blood sugar. It is important that you learn which symptoms of low blood sugar you usually have so that you can treat it quickly.

Symptoms of hypoglycemia (low blood sugar) include anxiety; behavior change similar to being drunk; blurred vision; cold sweats; confusion; cool, pale skin; difficulty with thinking; drowsiness; excessive hunger; fast heartbeat; headache (continuing); nausea; nervousness; nightmares; restless sleep; shakiness; slurred speech; or unusual tiredness or weakness.

If symptoms of low blood sugar occur, eat glucose tablets or gel, corn syrup, honey, or sugar cubes; or drink fruit juice, non-diet soft drink, or sugar dissolved in water. Also, check your blood for low blood sugar. Glucagon is used in emergency situations when severe symptoms such as seizures (convulsions) or unconsciousness occur. Have a glucagon kit available, along with a syringe or needle, and know how to use it. The members of your household also should know how to use it.

High blood sugar (hyperglycemia) is another problem related to uncontrolled diabetes. Symptoms of mild high blood sugar appear more slowly than those of low blood sugar. These may include blurred vision; drowsiness; dry mouth; flushed, dry skin; fruit-like breath odor; increased urination (frequency and volume); ketones in the urine; loss of appetite; sleepiness; stomachache, nausea or vomiting; tiredness; troubled breathing (rapid and deep); unconsciousness; or unusual thirst.

High blood sugar may occur if you do not exercise as much as usual, have a fever or infection, do not take enough or skip a dose of your diabetes medicine, or overeat or do not follow your meal plan.

If symptoms of high blood sugar occur, check your blood sugar level and then call your doctor for instructions.

This medicine is only part of a complete program for controlling diabetes. It is important that you always eat a healthy diet, watch your weight, and get regular exercise.

Riomet Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

• Abdominal or stomach discomfort


• cough or hoarseness


• decreased appetite


• diarrhea


• fast or shallow breathing


• fever or chills


• general feeling of discomfort


• lower back or side pain


• muscle pain or cramping


• painful or difficult urination


• sleepiness

Less common

• Anxiety


• blurred vision


• chest discomfort


• cold sweats


• coma


• confusion


• cool, pale skin


• depression


• difficult or labored breathing


• dizziness


• fast, irregular, pounding, or racing heartbeat or pulse


• feeling of warmth


• headache


• increased hunger


• increased sweating


• nausea


• nervousness


• nightmares


• redness of the face, neck, arms, and occasionally, upper chest


• seizures


• shakiness


• shortness of breath


• slurred speech


• tightness in the chest


• unusual tiredness or weakness


• wheezing

Rare

• Behavior change similar to being drunk


• difficulty with concentrating


• drowsiness


• lack or loss of strength


• restless sleep


• unusual sleepiness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

• Acid or sour stomach


• belching


• bloated


• excess air or gas in the stomach or intestines


• full feeling


• heartburn


• indigestion


• loss of appetite


• metallic taste in the mouth


• passing of gas


• stomachache


• stomach upset or pain


• vomiting


• weight loss

Less common

• Abnormal stools


• bad, unusual, or unpleasant (after) taste


• change in taste


• difficulty with moving


• discoloration of the fingernails or toenails


• flu-like symptoms


• joint pain


• rash


• runny nose


• sneezing


• stuffy nose


• swollen joints

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Riomet side effects (in more detail)

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More Riomet resources

• Riomet Side Effects (in more detail)
• Riomet Use in Pregnancy & Breastfeeding
• Riomet Drug Interactions
• Riomet Support Group
• 0 Reviews for Riomet - Add your own review/rating

• Riomet Prescribing Information (FDA)


• Riomet Consumer Overview


• Riomet Solution MedFacts Consumer Leaflet (Wolters Kluwer)


• Fortamet Prescribing Information (FDA)


• Glucophage Prescribing Information (FDA)


• Glucophage Consumer Overview


• Glucophage MedFacts Consumer Leaflet (Wolters Kluwer)


• Glucophage XR Extended-Release Tablets MedFacts Consumer Leaflet (Wolters Kluwer)


• Glucophage XR Prescribing Information (FDA)


• Glumetza Prescribing Information (FDA)


• Metformin Prescribing Information (FDA)


• Metformin Hydrochloride Monograph (AHFS DI)

Compare Riomet with other medications

• Diabetes, Type 2
• Insulin Resistance Syndrome