Sunday, 27 September 2009

Unidazol




Unidazol may be available in the countries listed below.


Ingredient matches for Unidazol



Secnidazole

Secnidazole is reported as an ingredient of Unidazol in the following countries:


  • Venezuela

International Drug Name Search

Wednesday, 23 September 2009

Zofenopril




Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

C09AA15,C09BA15

CAS registry number (Chemical Abstracts Service)

0081872-10-8

Chemical Formula

C22-H23-N-O4-S2

Molecular Weight

429

Therapeutic Category

ACE inhibitor

Chemical Names

(4S)-N-[(2S)-3-Benzoylthio-2-methylpropionyl]-4-phenylthio-L-prolin (IUPAC)

(4S)-N-[(S)-3-Mercapto-2-methylpropionyl]-4-(phenylthio)-L-proline benzoate (ester) (WHO)

L-Proline, 1-(3-(benzoylthio)-2-methyl-1-oxopropyl)-4-(phenylthio)-, (1(R*),2alpha,4alpha)-

Foreign Names

  • Zofenoprilum (Latin)
  • Zofenopril (German)
  • Zofénopril (French)
  • Zofenopril (Spanish)

Generic Names

  • Zofenopril (OS: BAN)
  • Zofénopril (OS: DCF)
  • Zofenopril Calcium (OS: BANM, USAN)
  • SQ 26991 (IS: Squibb)
  • Zoprace (IS: BMS)

Brand Names

  • Zocardis
    Berlin-Chemie, Russian Federation


  • Zofecard
    Menarini, Serbia


  • Zofenil
    Menarini, Ireland; Menarini, Luxembourg


  • Zofistar
    Berlin-Chemie, Lithuania; Berlin-Chemie, Latvia


  • Bifril Plus (Zofenopril and Hydrochlorothiazid)
    Berlin-Chemie, Germany


  • Bifril
    Berlin-Chemie, Germany; Biotoscana, Colombia; Leti, Venezuela; Lusofarmaco, Italy; Menarini, Austria


  • Bifrizide (Zofenopril and Hydrochlorothiazide)
    Lusofarmaco, Italy


  • Zantipress
    Firma, Italy


  • Zofaril
    Berlin-Chemie, Slovakia


  • Zofenil Diu (Zofenopril and Hydrochlorothiazide)
    Menarini, Spain


  • Zofenil
    Berlin-Chemie, Germany; Berlin-Chemie, Poland; Menarini, Austria; Menarini, Switzerland; Menarini, France; Menarini, Portugal


  • Zofenil plus (Zofenopril and Hydrochlorothiazide)
    Berlin-Chemie, Germany; Menarini, Austria; Menarini, Switzerland


  • Zofenilduo (Zofenopril and Hydrochlorothiazide)
    Menarini, France


  • Zofepril
    Menarini, Greece; Menarini, Luxembourg


  • Zofil
    Dr. Fisher, Netherlands; EU-Pharma, Netherlands; Menarini, Netherlands


  • Zofistar
    Berlin-Chemie, Estonia


  • Zopranol Diu (Zofenopril and Hydrochlorothiazide)
    Guidotti, Spain


  • Zopranol
    Guidotti, Italy; Menarini, Luxembourg


  • Zoprazide (Zofenopril and Hydrochlorothiazide)
    Guidotti, Italy


  • Zoprotec
    I.E. Ulagay, Turkey

International Drug Name Search

Glossary

BANBritish Approved Name
BANMBritish Approved Name (Modified)
DCFDénomination Commune Française
IUPACInternational Union of Pure and Applied Chemistry
ISInofficial Synonym
OSOfficial Synonym
Rec.INNRecommended International Nonproprietary Name (World Health Organization)
USANUnited States Adopted Name
WHOWorld Health Organization

Click for further information on drug naming conventions and International Nonproprietary Names.

Saturday, 19 September 2009

Bontril PDM


Generic Name: phendimetrazine (Oral route)


fen-dye-MET-ra-zeen TAR-trate


Commonly used brand name(s)

In the U.S.


  • Bontril

  • Bontril PDM

  • Bontril Slow-Release

  • Melfiat

  • Obezine

  • Phendiet

  • Phendiet-105

  • Prelu-2

Available Dosage Forms:


  • Tablet

  • Capsule

  • Capsule, Extended Release

Therapeutic Class: Appetite Suppressant, Centrally Acting


Chemical Class: Phendimetrazine


Uses For Bontril PDM


Phendimetrazine is used as part of a short-term plan, along with a low calorie diet, for weight reduction. It is used in obese patients who have not been able to lose weight with diet and exercise alone. Phendimetrazine belongs to the group of medicines known as appetite suppressants.


This medicine is available only with your doctor's prescription.


Before Using Bontril PDM


In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:


Allergies


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.


Pediatric


Appropriate studies have not been performed on the relationship of age to the effects of phendimetrazine tablets in the pediatric population. Safety and efficacy have not been established.


Use of phendimetrazine slow-release capsules is not recommended in children younger than 12 years of age.


Geriatric


No information is available on the relationship of age to the effects of phendimetrazine in geriatric patients.


Breast Feeding


There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.


Interactions with Medicines


Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.


Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.


  • Brofaromine

  • Clorgyline

  • Furazolidone

  • Iproniazid

  • Isocarboxazid

  • Lazabemide

  • Linezolid

  • Moclobemide

  • Nialamide

  • Pargyline

  • Phenelzine

  • Procarbazine

  • Rasagiline

  • Selegiline

  • Sibutramine

  • Toloxatone

  • Tranylcypromine

Interactions with Food/Tobacco/Alcohol


Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.


Other Medical Problems


The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:


  • Agitated state or

  • Arteriosclerosis (hardening of the arteries), advanced or

  • Drug abuse or dependence, history of or

  • Glaucoma or

  • Heart problems (e.g., heart murmur, valvular heart disease) or

  • Hypertension (high blood pressure), moderate to severe or

  • Hyperthyroidism (overactive thyroid)—Should not be used in patients with these conditions.

  • Hypertension (high blood pressure), mild—Use with caution. May make these conditions worse.

Proper Use of phendimetrazine

This section provides information on the proper use of a number of products that contain phendimetrazine. It may not be specific to Bontril PDM. Please read with care.


Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much is taken, it may become habit-forming (causing mental or physical dependence).


This medicine is available in two forms: slow-release capsules and tablets. Ask your doctor which dosage form is right for you.


Carefully follow your doctor's instructions for a reduced-calorie diet plan and regular exercise. Talk with your doctor before starting any exercise program.


Dosing


The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.


The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.


  • For treatment of obesity:
    • For oral dosage form (slow-release capsules):
      • Adults and teenagers—One capsule or 105 milligrams (mg) once a day, taken 30 to 60 minutes before the morning meal.

      • Children younger than 12 years of age—Use is not recommended.


    • For oral dosage form (tablets):
      • Adults—One tablet or 35 milligrams (mg) two or three times a day, taken one hour before meals. Your doctor may adjust your dose as needed. However, the dose is usually not more than 2 tablets three times a day.

      • Children—Use and dose must be determined by your doctor.



Missed Dose


If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.


Storage


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.


Keep out of the reach of children.


Do not keep outdated medicine or medicine no longer needed.


Ask your healthcare professional how you should dispose of any medicine you do not use.


Precautions While Using Bontril PDM


It is very important that your doctor check your progress at regular visits to make sure that this medicine is working properly and does not cause any unwanted effects.


Do not use phendimetrazine if you are also using similar medicines such as benzphetamine, diethylpropion, mazindol, phentermine, Didrex®, or Suprenza™. Also, do not use this medicine if you have used an MAO inhibitor (MAOI) such as Eldepryl®, Marplan®, Nardil®, or Parnate® within the past 14 days. Using these medicines together may cause serious unwanted effects.


Make sure your doctor knows if you are pregnant or planning to become pregnant before using this medicine.


This medicine may be habit-forming. If you think this medicine is not working properly after you have taken it for a few weeks, do not increase the dose. Instead, check with your doctor.


Stop using this medicine and check with your doctor right away if you notice a decrease in your ability to exercise, if you faint, or if you have chest pain, swelling of your feet or lower legs, or trouble with breathing. These may be symptoms of a very serious heart or lung problem.


This medicine may cause some people to become dizzy, lightheaded, or less alert than they are normally. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are dizzy or not alert.


For diabetic patients: This medicine may affect blood sugar levels. If you notice a change in the results of your blood or urine sugar tests or if you have any questions, check with your doctor.


Do not take other medicines unless they have been discussed with your doctor. This includes prescription and nonprescription (over-the-counter) medicines, dietary supplements, herbal remedies, or medicines for appetite control, asthma, colds, cough, hay fever, and sinus problems.


Bontril PDM Side Effects


Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.


Check with your doctor immediately if any of the following side effects occur:


Rare
  • Seeing, hearing, or feeling things that are not there

  • severe mental changes

Incidence not known
  • Anxiety

  • burning while urinating

  • difficult or painful urination

  • dizziness

  • dry mouth

  • fast, irregular, pounding, or racing heartbeat or pulse

  • feeling of warmth

  • headache

  • hyperventilation

  • increased need to urinate

  • irritability

  • nervousness

  • numbness or tingling in the arms or legs

  • passing urine more often

  • redness of the face, neck, arms, and occasionally, upper chest

  • restlessness

  • shakiness in the legs, arms, hands, or feet

  • shortness of breath

  • sweating

  • trembling or shaking of the hands or feet

  • trouble sleeping

  • trouble thinking, speaking, or walking

  • weakness

Get emergency help immediately if any of the following symptoms of overdose occur:


Symptoms of overdose
  • Abdominal or stomach cramps

  • blurred vision

  • change in consciousness

  • convulsions

  • diarrhea

  • discouragement

  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position

  • fainting

  • fast, slow, or irregular heartbeat

  • feeling sad or empty

  • lack of appetite

  • lightheadedness

  • loss of consciousness

  • loss of interest or pleasure

  • nausea

  • overactive reflexes

  • panic

  • physical attempt to injure

  • pounding in the ears

  • rapid breathing

  • sweating

  • tiredness

  • trouble concentrating

  • unusual tiredness or weakness

  • violent actions

  • vomiting

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:


Incidence not known
  • Decreased interest in sexual intercourse

  • difficulty having a bowel movement (stool)

  • inability to have or keep an erection

  • increased in sexual ability, desire, drive, or performance

  • increased interest in sexual intercourse

  • loss in sexual ability, desire, drive, or performance

  • sleeplessness

  • stomach pain

  • unable to sleep

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.


Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.



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Tuesday, 15 September 2009

Ursogal




Ursogal may be available in the countries listed below.


In some countries, this medicine may only be approved for veterinary use.

Ingredient matches for Ursogal



Ursodeoxycholic Acid

Ursodeoxycholic Acid is reported as an ingredient of Ursogal in the following countries:


  • United Kingdom

International Drug Name Search

Sunday, 13 September 2009

Cebion plus Rutin




Cebion plus Rutin may be available in the countries listed below.


Ingredient matches for Cebion plus Rutin



Ascorbic Acid

Ascorbic Acid is reported as an ingredient of Cebion plus Rutin in the following countries:


  • Austria

Rutoside

Rutoside is reported as an ingredient of Cebion plus Rutin in the following countries:


  • Austria

International Drug Name Search

Saturday, 12 September 2009

Predonine




Predonine may be available in the countries listed below.


Ingredient matches for Predonine



Prednisolone

Prednisolone is reported as an ingredient of Predonine in the following countries:


  • Japan

Prednisolone 21-(sodium succinate) (a derivative of Prednisolone) is reported as an ingredient of Predonine in the following countries:


  • Japan

Prednisolone 21-acetate (a derivative of Prednisolone) is reported as an ingredient of Predonine in the following countries:


  • Japan

International Drug Name Search

Erivedge


Erivedge is a brand name of vismodegib, approved by the FDA in the following formulation(s):


ERIVEDGE (vismodegib - capsule; oral)



  • Manufacturer: GENENTECH

    Approval date: January 30, 2012

    Strength(s): 150MG [RLD]

Has a generic version of Erivedge been approved?


No. There is currently no therapeutically equivalent version of Erivedge available.


Note: Fraudulent online pharmacies may attempt to sell an illegal generic version of Erivedge. These medications may be counterfeit and potentially unsafe. If you purchase medications online, be sure you are buying from a reputable and valid online pharmacy. Ask your health care provider for advice if you are unsure about the online purchase of any medication.

See also: About generic drugs.




Related Patents

There are no current U.S. patents associated with Erivedge.

Related Exclusivities

Exclusivity is exclusive marketing rights granted by the FDA upon approval of a drug and can run concurrently with a patent or not. Exclusivity is a statutory provision and is granted to an NDA applicant if statutory requirements are met.

  • Exclusivity expiration dates:
    • January 30, 2017 - NEW CHEMICAL ENTITY

See also...

  • Erivedge Consumer Information (Drugs.com)

Friday, 11 September 2009

Sulfinpyrazone




In the US, Sulfinpyrazone (sulfinpyrazone systemic) is a member of the drug class antigout agents and is used to treat Gouty Arthritis.

US matches:

  • Sulfinpyrazone

Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

M04AB02

CAS registry number (Chemical Abstracts Service)

0000057-96-5

Chemical Formula

C23-H20-N2-O3-S

Molecular Weight

404

Therapeutic Category

Uricosuric agent

Chemical Name

3,5-Pyrazolidinedione, 1,2-diphenyl-4-[2-(phenylsulfinyl)ethyl]-

Foreign Names

  • Sulfinpyrazonum (Latin)
  • Sulfinpyrazon (German)
  • Sulfinpyrazone (French)
  • Sulfinpirazona (Spanish)

Generic Names

  • Sulfinpirazone (OS: DCIT)
  • Sulfinpyrazone (OS: JAN, DCF, BAN)
  • G 28315 (IS)
  • Sulphinpyrazone (IS)
  • Sulfinpyrazon (PH: Ph. Eur. 6)
  • Sulfinpyrazone (PH: BP 2010, JP XIV, USP 32, Ph. Eur. 6)
  • Sulfinpyrazonum (PH: Ph. Eur. 6)

Brand Names

  • Anturan
    Amdipharm, United Kingdom; Cisuba, Sudan; Heko, Tanzania; Lindsay-Chemie, Zimbabwe; Medview, Ghana; Novartis, Guyana; Novartis, Israel; Novartis, Kenya; Novartis, Libya; Novartis, Nigeria


  • Anturane
    Novartis, United States


  • Apo-Sulfinpyrazone
    Apotex, Canada


  • Enturen
    Medivis, Italy


  • Sulfin
    TTY Biopharm, Taiwan

International Drug Name Search

Glossary

BANBritish Approved Name
DCFDénomination Commune Française
DCITDenominazione Comune Italiana
ISInofficial Synonym
JANJapanese Accepted Name
OSOfficial Synonym
PHPharmacopoeia Name
Rec.INNRecommended International Nonproprietary Name (World Health Organization)

Click for further information on drug naming conventions and International Nonproprietary Names.

Tuesday, 8 September 2009

Zalbion




Zalbion may be available in the countries listed below.


Ingredient matches for Zalbion



Tetryzoline

Tetryzoline hydrochloride (a derivative of Tetryzoline) is reported as an ingredient of Zalbion in the following countries:


  • Poland

International Drug Name Search

Friday, 4 September 2009

Icaden




Icaden may be available in the countries listed below.


Ingredient matches for Icaden



Isoconazole

Isoconazole is reported as an ingredient of Icaden in the following countries:


  • Colombia

  • Dominican Republic

Isoconazole nitrate (a derivative of Isoconazole) is reported as an ingredient of Icaden in the following countries:


  • Brazil

  • Colombia

  • Dominican Republic

  • Mexico

  • Peru

International Drug Name Search